la ricetta della cocaina

[coldd]

visto che in molti tread è menzionata, mi è venuto qst dubbio

so che deriva dalla pianta di coca, ma che procedimento usano x farla diventare polverina bianca?

[Fil9998]

questo non lo so ... so solo che le foglie solo "masticate" come fanno sulle Ande hanno tutt'altro effetto ...
anzi hanno un effetto proprio curativo per molte cose le foglie di coca ....
ma pure la cannabis ...

è che son "medicine " e potenti 'ste piante non van usate per scopi "ricreativi", ma per scopi curativi da chi lo sa fare e per i casi strettamente necessari .... tanto meno van alterate con chimiche varie etc, etc ...

[massimo78]

La cocaina è un composto chimico derivato dalle foglie di coca, una pianta che cresce sulle Ande, in America del Sud.

Aldilà di questo mi sembra un cacathread
basta cercare su google.

[coldd]

Originariamente inviato da massimo78

Aldilà di questo mi sembra un cacathread

[3NR1C0]

Clone-thread vorrai dire...

Arrivederci a tra qualche giorno

[Vin81]

la cocaina viene usata anche a scopo terapeutico, per esempio per calmare dolori fortissimi

[alphacygni]

se non fosse vietato, avrei gia' aperto "la ricetta della coccoina"

[giovane acero]

Originariamente inviato da alphacygni

se non fosse vietato, avrei gia' aperto "la ricetta della coccoina"

O anche 'la micetta della cocaina' con la foto di un felino flashato...

...aah bei tempi...

[dupa]

Originariamente inviato da Vin81

la cocaina viene usata anche a scopo terapeutico, per esempio per calmare dolori fortissimi

al massimo si usa la morfina. la cocaina di solito viene usata per anestetizzare.

[SaettaC]

Lo sapete che c'ero, no?

edit: eh, sì, bei tempi... dovrebbero consentire un clone-thread o caca-thread a bimestre-trimestre ad utente...

[alphacygni]

Originariamente inviato da giovane acero

O anche 'la micetta della cocaina' con la foto di un felino flashato...

...aah bei tempi...

gia'....

[FreeMan]

nonostante il titolo da clone3d cmq la domanda posta mi pare sensata.. quindi, astenersi chi vuole solo postare "clone 3d " ecc...

rispondere seriamente, tnx

>bYeZ<

[massimo78]

Originariamente inviato da giovane acero

O anche 'la micetta della cocaina' con la foto di un felino flashato...

...aah bei tempi...

beh anche il rospo con la sigaretta non è male

[dupa]

Qui dice tutto: http://en.wikipedia.org/wiki/Cocaine
anche di quando il Papa si beveva il vino aromatizzato alla cocaina

[giovane acero]

The basic formula for cocaine starts by purchasing or making tropinone,
converting the tropinone into 2-carbomethoxytropinone (also known as
methyl-tropan-3-one-2-carboxylate), reducing this to ecgonine, and
changing that to cocaine. Sounds easy? It really is not very simple, but
with Reagan's new drug policies, cracking down on all of the drug
smuggling at the borders, this synthetic cocaine may be the source of
the future. This synthesis is certainly worth performing with the high
prices that cocaine is now commanding. As usual, I will start with the
precursors and intermediates leading up to the product.

Succindialdehyde. This can be purchased, too. 23.2 g of
succinaldoxime powder in 410 ml of 1 N sulfuric acid and add dropwise
with stirring at 0¡ a solution of 27.6 g of sodium nitrite in 250 ml of
water over 3 hours. After the addition, stir and let the mixture rise to
room temp for about 2 hours, taking care not to let outside air into the
reaction. Stir in 5 g of Ba carbonate and filter. Extract the filtrate
with ether and dry, evaporate in vacuo to get the succindialdehyde. This
was taken from JOC, 22, 1390 (1957). To make succinaldoxime, see JOC,
21, 644 (1956).

Complete Synthesis of Succindialdehyde. JACS, 68, 1608 (1946). In a 2
liter 3 necked flask equipped with a stirrer, reflux condenser, and an
addition funnel, is mixed 1 liter of ethanol, 67 g of freshly distilled
pyrrole, and 141 g of hydroxylamine hydrochloride. Heat to reflux until
dissolved, add 106 g of anhydrous sodium carbonate in small portions as
fast as reaction will allow. Reflux for 24 hours and filter the mixture.
Evaporate the filtrate to dryness under vacuo. Take up the residue in
the minimum amount of boiling water, decolorize with carbon, filter and
allow to recrystallize in refrigerator. Filter to get product and
concentrate to get additional crop. Yield of succinaldoxime powder is a
little over 40 g, mp is 171-172¡.

5.8 g of the above powder is placed in a beaker of 250 ml capacity and
54 ml of 10% sulfuric acid is added. Cool to 0¡ and add in small
portions of 7 g of sodium nitrite (if you add the nitrite too fast,
nitrogen dioxide fumes will evolve). After the dioxime is completely
dissolved, allow the solution to warm to 20¡ and effervescence to go to
completion. Neutralize the yellow solution to litmus by adding small
portions of barium carbonate. Filter off the barium sulfate that
precipitates. The filtrate is 90% pure succindialdehyde and is not
purified further for the reaction to create tropinone. Do this procedure
3 more times to get the proper amount for the next step, or multiply the
amounts given by four and proceed as described above.

Take the total amount of succinaldehyde (obtained from 4 of the above
syntheses combined) and without further treatment or purification (this
had better be 15.5 g of succindialdehyde) put into an Erlenmeyer flask
of 4-5 liters capacity. Add 21.6 g of methylamine hydrochloride, 46.7 g
of acetonedicarboxylic acid, and enough water to make a total volume of
2 liters. Adjust the pH to 8-10 by slowly adding a saturated solution of
disodium phosphate. The condensate of this reaction (allow to set for
about 6 days) is extracted with ether, the ethereal solution is dried
over sodium sulphate and distilled, the product coming over at 113¡ at
25 mm of pressure is collected. Upon cooling, 14 g of tropinone
crystallizes in the pure state. Tropinone can also be obtained by
oxidation of tropine with potassium dichromate, but I could not find the
specifics for this operation.

2-Carbomethoxytropinone. A mixture of 1.35 g of sodium methoxide (this
is sodium in a minimum amount of methanol), 3.5 g of tropinone, 4 ml of
dimethylcarbonate and 10 ml of toluene is refluxed for 30 min. Coo] to
0¡ and add 15 ml of water that contains 2.5 g of ammonium chloride.
Extract the solution after shaking with four 50 ml portions of
chloroform, dry, evaporate the chloroform in vacuo. Dissolve the oil
residue in 100 ml of ether, wash twice with a mixture of 6 ml of
saturated potassium carbonate and three ml of 3 N KOH. Dry and evaporate
in vacuo to recover the unreacted tropinone. Take up the oil in a
solution of aqueous ammonium chloride and extract with chloroform, dry,
and evaporate in vacuo to get an oil. The oil is dissolved in hot
acetone, cool, and scratch inside of flask with glass rod to precipitate
2- carbomethoxytropinone. Recrystallize 16 g of this product in 30 ml of
hot methyl acetate and add 4 ml of cold water and 4 ml of acetone. Put
in freezer for 2l/2 to 3 hours. Filter and wash the precipitate with
cold methyl acetate to get pure product.

Methylecgonine. 0.4 mole of tropinone is suspended in 80 ml of ethanol
in a Parr hydrogenation flask (or something that can take 100 psi and
not react with the reaction, like stainless steel or glass). 10 g of
Raney Nickle is added with good agitation (stirring or shaking) followed
by 2- 3 ml of 20% NaOH solution. Seal vessel, introduce 50 psi of
hydrogen atmosphere (after flushing vessel with hydrogen) and heat to
40-50¡. After no more uptake of hydrogen (pressure gauge will hold
steady after dropping to its lowest point) bleed off pressure and filter
the nickle off, rinse out bottle with chloroform and use this rinse to
rinse off the nickle while still on the filter paper. Make the filtrate
basic with KOH after cooling to 10¡. Extract with chloroform dry, and
evaporate the chloroform in vacuo to get an oil. Mix the oil plus any
precipitate with an equal volume of dry ether and filter. Add more dry
ether to the filtrate until no more precipitate forms, filter and add to
the rest of the precipitate. Recrystallize from isopropanol to get pure
methylecgonine. Test for activity. If active, skip down to the step for
cocaine. If not active, proceed as follows. Stir with activated carbon
for 30 min, filter, evaporate in vacuo, dissolve the brown liquid in
methanol, and neutralize with 10% HCI acid in dry ether. Evaporate the
ether until the two layers disappear, and allow to stand for 2 hours at
0¡ to precipitate the title product. There are many ways to reduce
2-carbomethoxytropinone to methylecgonine. I chose to design a Raney
Nickle reduction because it is cheap and not as suspicious as LAH and it
is much easier than zinc or sodium amalgams.

Cocaine. 4.15 g of methylecgonine and 5.7 g of benzoic anhydride in 150
ml of dry benzene are gently refluxed for 4 hours taking precaution
against H20 in the air (drying tube). Cool in an ice bath, acidify
carefully with hydrochloric acid, dry, and evaporate in a vacuum to get
a red oil which is treated with a little portion of isopropanoi to
precipitate cocaine.

As you can see, this is quite a chore. The coca leaves give ecgonine,
which as you can see, is only a Jump away from cocaine. If you can get
egconine, then dissolve 8l/2 g of it in 100 ml of ethanol and pass
(bubble) dry HC1 gas through this solution for 30 min. Let cool to room
temp and let stand for another 11/2 hours. Gently reflux for 30 min and
evaporate in vacuo. Basify the residue oil with NaOH and filter to get
8.4 g of methylecgonine, which is converted to cocaine as in the cocaine
step above.

Below is given a somewhat easier method of producing tropinone by the
general methods of Willstatter, who was instrumental in the first
synthetic production of cocaine and several other alkaloids. After
reviewing this method, I found it to be simpler than the above in many
respects.

Tropinone. 10 g of pyrrolidinediethyl diacetate are heated with 10 g of
cymene and 2 g of sodium powder, the reaction taking place at about
160¡. During the reaction (which is complete in about 10 min) the temp
should not exceed 172¡. The resulting reaction product is dissolved in
water, then saturated with potassium carbonate, and the oil, which
separates, is boiled with dilute sulfuric acid. 2.9 g of tropinone
picrate forms and is filtered.

Here are two more formulas devised by Willstatter that produce tropinone
from tropine. Take note of the yield differences.

Tropinone. To a solution of 25 g tropine, dissolved in 10 times its
weight of 20% sulfuric acid are added 25 g of a 4% solution of potassium
permanganate in 2 or 3 g portions over 45 min while keeping the temp at
10-12¡. The addition of permanganate will cause heat (keep the temp
10-12¡) and precipitation of manganese dioxide. The reaction mixture is
complete in I hour. A large excess of NaOH is added and the reaction is
steam distilled until I liter of distillate has been collected. The
tropinone is isolated as the dibenzal compound by mixing the distillate
with 40 g of benzaldehyde in 500 cc of alcohol and 40 g of 10% sodium
hydroxide solution. Let stand several days to get dibenzaltropinone as
yellow needles. Yield: 15.5 g, 28%. Recrystallize from ethanol to
purify.

Tropinone. A solution of 12 g of chromic acid in the same amount of
water (12 g) and 60 g of glacial acetic acid is added dropwise with
stirring over a period of 4 hours to a solution of 25 g of tropine in
500 cc of glacial acetic acid that has been warmed to 60-70¡ and is
maintained at this temp during the addition. Heat the mixture for a
short time on a steam bath until all the chromic acid has disappeared,
cool and make strongly alkaline with NaOH. Extract with six 500 cc
portions of ether and evaporate the ether in vacuo to get an oil that
crystallizes readily. Purify by converting to the picrate or
fractionally distill, collecting the fraction at 224-225¡ at 714 mm
vacuo.

The tropinones can be used in the above formula (or in a formula that
you have found elsewhere) to be converted to cocaine. Remember to
recrystallize the 2-carbomethoxytropinone before converting to
methylecgonine.

semplice no?
quando avete finito riordinate la cucina che poi mamma s'incazza

[FastFreddy]

Originariamente inviato da Vin81

la cocaina viene usata anche a scopo terapeutico, per esempio per calmare dolori fortissimi

Quella non è la morfina? (Oppiaceo affine all'eroina)

Le foglie di coca dovrebbero solo alleviare la fatica...

[beppegrillo]

Originariamente inviato da coldd

visto che in molti tread è menzionata, mi è venuto qst dubbio

so che deriva dalla pianta di coca, ma che procedimento usano x farla diventare polverina bianca?

3gg di sospensione

>byez<

[coldd]

Originariamente inviato da FreeMan

nonostante il titolo da clone3d cmq la domanda posta mi pare sensata.. quindi, astenersi chi vuole solo postare "clone 3d " ecc...

rispondere seriamente, tnx

>bYeZ<

il giudice mi ha dato ragione



cmq era (anche) una domanda seria

[giovane acero]

Oh, naturalmente quello di prima è il processo per ottenere cocaina interamente 'sintetica' qui sotto c'è, invece, il processo normale...

buona lettura e anche in questo caso ricordatevi di sistemare bene la cucina una volta che avete terminato la preparazione.


It takes 100 to 150 kilograms of dry leaves to produce one kilogram of dry paste. The leaves are soaked in water, a strong alkali like lime is added to release the alkaloids, and a solvent like kerosene or petrol/diesel is stirred in to dissolve the alkaloids. The solvent does not mix with the water. The solvent is separated from the water by draining the water out the bottom of the container and pouring the solvent out the top. Thereafter, sulphuric acid is added to separate out the alkaloids. The remaining paste is separated from the solvent by means of filtration and dried in the sun.

Next, the paste is converted into a base. This process usually takes place in a ‘base lab’. This phase determines the quantities and proportions of different alkaloids in the end product. The conversion involves dissolving the paste in water and adding sulphuric acid to it to further acidify the solution. Potassium permanganate is added to the solution, causing oxidation which destroys [?] the oils and impurities almost immediately. Cocaine hydrochloride made from properly oxidized base can consist of as much as 82 per cent cocaine base.

The last step of the process is to convert the base into ‘crystal’, the South American term for cocaine hydrochloride. The base is dissolved in ether, and hydrochloric acid is added to separate out the cocaine hydrochloride crystals. Once the crystals have been collected by means of filtration, they are dried. This process is rarely carried out with less than three kilograms of base, and as much as 50 kilograms can be converted at one time.

Crack and cocaine freebase is cocaine base obtained from cocaine hydrochloride or paste. Crack has largely replaced cocaine freebase. While cocaine hydrochloride is sniffed/snorted, crack is smoked.

[dooka]

Blow aiuta in questo.
Vengono raccolte le foglie di cocaina, poi vengono pressate/passate tipo le olive e qualsiasi altro tipo di raccolto da cui se ne estra una composizione liquida.

Ne uscirà un misto tra la linfa e i principi attivi della cocaina (liquame bianco abbastanza denso)

Questo viene poi steso, tirato come fosse pasta su una tela finissima che viene posta sotto luce diretta al fine di essicare il tutto e lasciare il fondo che è la cocaina pura al 100%